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・ P2RX3
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P2X purinoreceptor
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P2X purinoreceptor : ウィキペディア英語版
P2X purinoreceptor

P2X receptors are a family of cation-permeable ligand gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). They belong to a larger family of receptors known as the purinergic receptors. P2X receptors are present in a diverse array of organisms including humans, mouse, rat, rabbit, chicken, zebrafish, bullfrog, fluke, and amoeba.
==Physiological roles==

P2X receptors are involved in a variety of physiological processes,〔 including:
* Modulation of cardiac rhythm and contractility
* Modulation of vascular tone
* Mediation of nociception, especially chronic pain
* Contraction of the vas deferens during ejaculation
* Contraction of the urinary bladder during micturition
* Platelet aggregation
* Macrophage activation
* Apoptosis
* Neuronal-glial integration

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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